Currently In Progress
Effect of Intense Multi-Modal Training on Bone Mineral Density, Bone Biomarkers, and Quality of Life in Persons with Spinal Cord Injury
This is a four year National Institute of Health (NIH) funded study for clients who are beginning an activity-based recovery program.
Men and women with a spinal cord injury will complete six months of exercise training, and a control group of individuals with spinal cord injury will also be recruited. All participants will undergo testing (DXA, blood draws, and various surveys) at baseline and three and six months of the study to assess changes in bone mineral density (BMD), bone turnover, body composition, and quality of life.
BMD will be obtained at the spine, hip, proximal tibia, distal femur, and whole body at baseline and after three and six months of training using dual-energy x-ray absorptiometry (DXA) via a commercially-available bone densitometer (GE Lunar Prodigy Advance). Fat mass and fat-free mass of the whole body, upper body, and leg will be assessed using DXA.
Blood draws (10 mL) will be obtained at the same time of day at baseline and at three and six months. Bone formation will be assessed via fasting serum osteocalcin (OC), and bone resorption will be assessed via fasting serum cross-linked N-telopeptide of type I collagen (NTx).
In all subjects, surveys will be used to measure quality of life at baseline and after three and six months of training. For more information on how to participate in this study, please Project Walk at Info@ProjectWalk.com
Upcoming Research Studies
To Be Announced